Peripheral nerve injury are common and the available treatments include surgical interventions that cannot achieve complete regeneration, in part due to slow rate of axonal growth. Those injuries involve serious health implications that are lifelong and are burden on the public health and economy. We design methods to accelerate axonal growth to improve regeneration after nerve injury, using remote control approach. To this end we are interested in combining materials design and the triggering of ion channels endogenously expressed in the peripheral nervous system, to control the axonal growth process. We are exploring mechanistic approaches to trigger axonal growth which are also clinically translatable.